TITLE:
Chronic Recurrent Multifocal Osteomyelitis (CRMO): An Unusual Presentation of Limb Pain
AUTHORS:
Khadiza Tul Qubra, Mujammel Haque, Mohammad Imnul Islam, Shahana Rahman
KEYWORDS:
Bone Pain, CRMO, Multifocal Osteomyelitis
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.12 No.3,
July
13,
2022
ABSTRACT: Chronic
recurrent multifocal osteomyelitis (CRMO), known as
nonbacterial osteomyelitis, is an autoinflammatory disease with periodic
exacerbations, also known as nonbacterial osteomyelitis. It is a rare,
noninfectious inflammatory disorder characterized by multifocal bony lesions
with pain. Conventional X-ray and CT imaging show multiple osteolytic and
sclerotic lesions in the affected limbs. It is a great challenge for pediatricians
to diagnose this disease for its rarity. Early diagnosis, regular follow-up and
appropriate treatments are mandatory to reduce morbidity and prevent these disease complications. We report here
two cases of CRMO who presented with pain, swelling and redness of multiple
sites of lower limbs from the Department of Paediatrics, Bangabandhu Sheikh Mujib Medical
University (BSMMU). Clinical features, laboratory findings, and
characteristic radiological findings were strongly suggestive of CRMO.