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Reddy, S., Thomas, L., Santoshkumar, K.S., Nayak, N., Mukhopadhyay, A. and Thangam, S. (2016) A LC-MS/MS Method with Column Coupling Technique for Simultaneous Estimation of Lamivudine, Zidovudine, and Nevirapine in Human Plasma. Journal of Analytical Science and Technology, 7, Article No. 17.
https://doi.org/10.1186/s40543-016-0097-2
has been cited by the following article:
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TITLE:
Development, Validation and Application of a Spectrofluorimetric Method for the Quantification of Nevirapine in Pharmaceutical Formulations Tablets and Suspensions
AUTHORS:
Lucien Murhula Namegabe, Aladin Ombeni Mahano, Serigne Omar Sarr
KEYWORDS:
Spectrofluorimetric Method, Validation Nevirapine, Sodium Hypochlorite
JOURNAL NAME:
American Journal of Analytical Chemistry,
Vol.13 No.6,
June
30,
2022
ABSTRACT: The development of the spectrofluorimetric method can be considered a promising alternative that is relatively less expensive and sufficiently reliable. In the current literature, no method for the analysis of nevirapine by spectro-fluorimetric has been reported. The proposed method is based on the transformation of naturally non-fluorescent nevirapine into a fluorescent derivative after chemical synthesis. Maximum excitation and emission wavelengths are 290 nm and 357 nm respectively. The analytical performance of the method demonstrates linearity in the concentration range 1.5 × 10-2 and 13.5 × 10-2 μg/mL with a correlation coefficient (r) greater than 0.999. The detection (LOD) and quantification (LOQ) limits found are 1.97 × 10-3 μg/mL and 5.48 × 10-3 μg/mL respectively. Recovery is achieved with 99.9% and 100.3% trueness, intra-day precision with a coefficient of variation of repeatability (CVr) of 0.99% and inter-day precision with a coefficient of variation of precision (CVR) of 1.7%. The method has been successfully applied in the analysis of 10 batches of nevirapine tablets and suspensions.