TITLE:
EON Therapy Ameliorates Cachexia and Quality of Life in Cancer Patients
AUTHORS:
Abhiram Kumar, Jyoti Sharma, Raktim Chattopadhyay, Shrikant Charde, Anubhab Mukherjee
KEYWORDS:
Cancer, Cachexia, Nutritional Intervention, EON Therapy, Quality of Life
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.13 No.7,
July
1,
2022
ABSTRACT: Cancer induced cachexia, a gross loss of skeletal muscle with or without
adipose tissue wasting, remains a clinical impasse resulting in poor prognosis
and Quality of Life (QoL). It is characterized by an inflammation driven
anorexia and aberrant energy and protein balance. Indubitably, nutritional rehabilitation
is required to address various daunting challenges of this multifactorial
syndrome. Esperer Onco Nutrition has come up with an optimal clinical nutrition
formulation with promising anti-cachexia effects. Towards validating the
efficacy and ensuring the safety of EON Therapy (Es-Invigour plus
Es-Fortitude-Protect) under clinical settings, a phase IV post marketing
surveillance (PMS) study with 63 patients from various hospitals across India
was undertaken. This multi-nutrient and multi-targeted nutritional
intervention, being concurrent with mainstream therapy, demonstrated potential
to ameliorate the cachectic condition which was measured by body weight of the
volunteers at each visit. Biochemical parameters improved or remained same.
Overall QoL assessment was performed by using ECOG Scale and Malnutrition
Screening Tool (MST) which showed significant improvement in physical wellness
and nutritional status of the volunteers. No adverse effect was observed during
the entire period. These observations reinforce the need of research based
nutritional intervention for clinical use in cachectic cancer patients.