TITLE:
Autonomic Function in Individuals with Slow Heart Rate Response following an Exercise Stress Test
AUTHORS:
Itai Goldfarb, Kobi Serr, Shlomo Segev, Joseph Shemesh, Ilan Goldenberg, Mickey Scheinowitz
KEYWORDS:
Heart Rate, Heart Rate Recovery, Heart Rate Variability, Exercise Stress Test
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.12 No.6,
June
14,
2022
ABSTRACT: Objective: To examine the autonomic function using HRV measures in apparently healthy individuals undergoing exercise stress test (EST) and demonstrating slow HRR response. Methods: HRV was measured with 12 lead ECGs during graded EST and analyzed via a post-processing method. Autonomic function was determined by Power Spectral Analysis of the very low frequency (VLF), low frequency (LF), high frequency (HF), and the ratio of LF/HF. We correlated HRV indices with resting, exercise, and recovery data. Results: No differences were found in anthropometric measurements, peak EST HR, and METS between individuals with slow HRR (below 18 b/min) compared with controls (HRR > 18 b/min). Only the VLF component of the HRV indices was statistically different (p = 0.03) at one-minute post-exercise compared with controls. Additionally, a significant correlation between HRR and resting LF and HF indices was found in the individuals with slow HRR but not in the controls. Conclusion: In apparently healthy individuals with slow HRR post-EST, autonomic function did not demonstrate any differences at any phase of the EST, including at one minute of recovery. However, a significant correlation was found between resting LF and HF powers and HRR in individuals with slow vagal reactivation post-exercise. The clinical and prognostic implications of such observation deserve further investigation.