TITLE:
Assessment of in Situ Anthelminthic Activity of Ethanolic Extract of Bidens pilosa against Adult’s Gastro-Intestinal Strongyle of Small Ruminants
AUTHORS:
Mbogning Tayo Gertrude, Yondo Jeannette, Tsila Henri Gabriel, Mpoame Mbida
KEYWORDS:
Gastro-Intestinal Strongyle, Bidens pilosa, Anthelminthic Activity, in Situ
JOURNAL NAME:
American Journal of Plant Sciences,
Vol.13 No.4,
April
11,
2022
ABSTRACT: Infections caused by gastrointestinal nematodes are
major threats to livestock industry in the developing countries. They cause
direct effects in form of loss in production and indirect economic losses due
to high cost of anthelmintic drugs. Various
alternative strategies are in practice to control parasitism which includes the usage of medicinal plants. This study evaluates the in situ anthelminthic activity of Bidens pilosa ethanolic extract on
gastro-intestinal strongyles of small ruminants. Twenty (20) naturally infested
goats of both sexes were distributed into 5 groups (n = 4) corresponding to
groups receiving Tween 80 at 2.8%, Albendazole at 5 mg/kg and the three doses
of extract (125, 250 and 500 mg/kg). The doses of extract and 2.8% Tween 80
were administered twice daily for 3 consecutive days while Albendazole was
administered in a single dose. Faecal eggs count reduction, body weight, packed
cell volume (PCV) and total worm count reduction were determined. Results
showed that the ethanolic extract of B. pilosa was not effective against
adult worms while Albendozole inflicted a 100% reduction of eggs count and
total worm count of digestive strongyle. Body weight and PCV remain almost
constant. This study indicates that ethanolic extract of B. pilosa at tested doses
has no anthelminthic activity. However, further optimization and standardization
of the ethanolic extract of B. pilosa could enhance its anthelminthic
activity.