TITLE:
Primitive Breast Lymphoma about a Case: Literature Review
AUTHORS:
Arouna Adama Doumbia, Maiga Amadou, Bah Amadou, Saye Zakari, Coulibaly Bourama, Diarra Bourama, Togo Adégné
KEYWORDS:
Breast Lymphoma, Diagnosis, Large Bcell Lymphoma, Chemotherapy
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.13 No.3,
March
31,
2022
ABSTRACT: Primary
breast lymphomas are rare. They are defined by the involvement of one or both
breasts. This is the first site affected or mainly affected with the exception
of ipsilateral axillary involvement. Due to the absence of specific clinical
and radiological signs, the diagnosis is confirmed by histology. The most
frequent entity remains diffuse large B-cell lymphomas. The place of surgery
remains exclusive in establishing the initial diagnosis. Anthracycline-based
chemotherapy with or without Rituximab remains the gold standard in the
therapeutic arsenal. We present the case of a 42-year-old woman with no
surgical history; nulliparous; followed in nephrology for chronic renal
failure, received as an outpatient for a nodule in the left breast in a context
of dyspnea. This is a nodule discovered incidentally during a routine
examination. Clinical examination of the left breast found nipple retraction
without ulceration; a mass 7 cm in diameter located in the left upper outer
quadrant. Breast ultrasound and mammography suggest a suspected lesion of
malignancy. After a percutaneous micro biopsy; the histological study confirms
the diagnosis of a large B-cell lymphoma of the left breast. A TAP CT scan is
performed as part of the extension assessment. Chemotherapy based on R-CHOP
with local radiotherapy is decided in CPR.