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Baum, T., Rohrmeier, A., Syväri, J., Diefenbach, M.N., Franz, D., Dieckmeyer, M., Scharr, A., Hauner, H., Ruschke, S., Kirschke, J.S. and Karampinos, D.C. (2018) Anatomical Variation of Age-Related Changes in Vertebral Bone Marrow Composition Using Chemical Shift Encoding-Based Water-Fat Magnetic Resonance Imaging. Frontiers in Endocrinology (Lausanne), 9, 141.
https://doi.org/10.3389/fendo.2018.00141

has been cited by the following article:

• TITLE: Quantitative Evaluation of Fat Composition in Lumbar Vertebral Body and Paraspinal Muscle by Proton Density Fat Fraction with MRI

  AUTHORS: Yuji Kasukawa, Michio Hongo, Toshihito Ebina, Taishi Chiba, Daisuke Kudo, Ryota Kimura, Yoichi Shimada, Naohisa Miyakoshi

  KEYWORDS: Proton Density Fat Fraction, Vertebral Body, Bone Marrow, Para-Spinal Muscle, Age, Bone Mineral Density

  JOURNAL NAME: Open Journal of Orthopedics, Vol.12 No.3, March 11, 2022

  ABSTRACT: Purpose: Bone marrow and muscle adiposity have been considered to correlate with osteoporosis and Sarcopenia. Proton Density Fat Fraction (PDFF) can be measured by Magnetic Resonance Imaging (MRI). The purpose of the present study was to measure PDFF in the lumbar spine, paraspinal muscle and subcutaneous fat tissue. Methods: Participants were comprised of 30 patients (18 males, 12 females; age range, 14 - 87 years) who underwent MRI due to low back symptoms. PDFFs for the body of the fourth lumbar vertebra (L4), paraspinal muscle, and subcutaneous fat were measured. Results: PDFFs of the vertebral body and subcutaneous fat were significantly higher than that of paraspinal muscle (p fat between females and males, PDFFs of the vertebral body and paraspinal muscle were significantly higher in older subjects (>63 years) than in younger subjects (Conclusions: PDFF of the vertebral body was significantly higher than that of paraspinal muscle. PDFFs of the vertebral body and paraspinal muscle were significantly lower in younger subjects than in older subjects.