TITLE:
Quantitative Evaluation of Fat Composition in Lumbar Vertebral Body and Paraspinal Muscle by Proton Density Fat Fraction with MRI
AUTHORS:
Yuji Kasukawa, Michio Hongo, Toshihito Ebina, Taishi Chiba, Daisuke Kudo, Ryota Kimura, Yoichi Shimada, Naohisa Miyakoshi
KEYWORDS:
Proton Density Fat Fraction, Vertebral Body, Bone Marrow, Para-Spinal Muscle, Age, Bone Mineral Density
JOURNAL NAME:
Open Journal of Orthopedics,
Vol.12 No.3,
March
11,
2022
ABSTRACT: Purpose: Bone marrow and muscle
adiposity have been considered to correlate
with osteoporosis and Sarcopenia. Proton Density Fat Fraction (PDFF) can
be measured by Magnetic Resonance Imaging (MRI). The purpose of the present
study was to measure PDFF in the lumbar spine, paraspinal muscle and
subcutaneous fat tissue. Methods: Participants were comprised of 30 patients (18 males, 12 females; age range, 14 - 87 years) who underwent
MRI due to low back symptoms. PDFFs
for the body of the fourth lumbar vertebra (L4), paraspinal muscle, and
subcutaneous fat were measured. Results: PDFFs of the vertebral body and
subcutaneous fat were significantly higher than that of paraspinal muscle (p
fat between females and males, PDFFs of the vertebral body and paraspinal muscle were significantly higher in
older subjects (>63 years) than in younger subjects (Conclusions: PDFF of the
vertebral body was significantly higher than that of paraspinal muscle.
PDFFs of the vertebral body and paraspinal muscle were significantly lower in
younger subjects than in older subjects.