TITLE:
Lymphadenectomy for Colorectal Cancer: Experience of the Brazzaville Teaching Hospital
AUTHORS:
Pierlesky Elion Ossibi, Murielle Etiennette Julie Note Madzele, Noé Hensnel Motoula Latou, Didace Massamba Miabaou, Prude Pertinie Avala, Jile Florient Mimiesse-Monamou, Arnaud Mongo-Onkouo, Rody Stéphane Ngami, Fabien Gael Mouamba, Eliane Ndounga, Alexis Fortuné Bolenga Liboko, Régis Franck Moyikoua, Freznel Ngoma Mabonzo, Apendi Philestine Clausina Ahoui, Gilbert Fabrice Otiobanda, Blaise Irénée Atipo Ibara
KEYWORDS:
Lymphadenectomy, Surgery, Cancer, Colorectal
JOURNAL NAME:
Surgical Science,
Vol.13 No.3,
March
8,
2022
ABSTRACT: Introduction: Lymph node (LN) metastasis are important biomarkers in the resection of colorectal cancer translating into
accurate disease staging. It is therefore obvious that lymph node
dissection in the curative treatment of colorectal
cancer is a prognostic factor that influences survival and guides management strategy. This study aims to evaluate lymph node dissection in
colorectal cancers (CRC) managed at the Teaching Hospital, Brazzaville, Congo. Patients
and Method: We carried out a descriptive prospective study
during a period of 18 months from October 2020 to March 2021 involving patients who underwent curative treatment for
colorectal cancer at the visceral surgery department of the Brazzaville
Teaching Hospital. Results: Thirty
(30) cases of CRC were recorded out of 738 hospitalizations in the
visceral surgery departments, which constitute 4.06% of the in-patient activity
of the department during the period under study. Mean age was 55.13 years and a
male predominance was observed with a sex
ratio of 1.14. Colonic involvement was predominant in our series and was
found in 22 of the patients. 25 patients underwent
surgical resection while 5 patients could not undergo operative treatment. 17 out of the 25 patients underwent curative treatment, 6 were
offered palliative care, whereas surgical abstention was decided in 2 patients.
The average number of lymphadenectomies per patient was 16.43. Lymphadenectomy
was greater than or equal to 12 in 88% of patients. Nine patients had vascular
emboli whereas 10 patients had perineural invasion. The tumor was staged as T3
in 15 patients; six patients had a negative lymph node and 11 patients had at
least one lymph node invasion. Distant metastasis status could not be
determined in 10 patients. Conclusion: Lymphadenectomy
is a hallmark in the curative treatment of colorectal cancer as it allows for
optimal staging. This represents a strong
prognostic factor that defines adjuvant therapy and overall patient
outcome.