TITLE:
Etiological Factors of Infective Endocarditis in Children Aged 1 Month to 15 Years Hospitalised in the Paediatric Department of CHU Gabriel Touré of Bamako (Mali)
AUTHORS:
Maiga Belco, Sacko Karamoko, Konaté Djéneba, Diakité Abdoul Aziz, Dembélé Adama, Cissé Mohamed Elmouloud, DansoKo Nassira, Traoré Kalilou, Togo Pierre, Doumbia Abdou Karim, Traoré Fousseini, Diakité Fatoumata Léonie, Sidibé Lalla, Maiga Leila, Ahmadou Ibrahim, Coulibaly Oumar, Diall Hawa, Sylla Mariam
KEYWORDS:
Infective Endocarditis, Etiological Factors, Pediatrics, Bamako
JOURNAL NAME:
World Journal of Cardiovascular Surgery,
Vol.12 No.2,
February
28,
2022
ABSTRACT: Introduction: In emerging countries where studies are rarer, the epidemiological
profile of infective endocarditis resembles that of developed countries at the
beginning of the antibiotic era. There is little data available in Mali on this
subject, motivating this study, the aim of which was to study the etiological
factors of infective endocarditis in children aged between 1 month and 15 years
hospitalised in the paediatric department of the CHU Gabriel Touré. Patients
and Methods: We conducted a cross-sectional and descriptive study, which
took place from August 2018 to August 2019 (13 months), in children aged between
1 month and 15 years hospitalised in the paediatric department of the Gabriel
Touré University Hospital with an ultrasound- confirmed
cardiac disease and a temperature above 38°C. Results: The
hospitalization rate was 0.4%. The average age was 11 months, the sex ratio was
1.35. Respiratory distress (63.6%) and fever (30.3%) were the most common
reasons for referral. Congenital heart disease (87.9%) and dyspnoea on feeding
(24.2%) were the most common medical histories. IVC was the most frequent
congenital heart disease (36.4%). The mean temperature was 39.1°C. Blood
cultures were taken in 24 patients (72.7%) and were positive in 27.3%. Staphylococcus aureus was found in 55.6%
of cases. Trans-thoracic ultrasound found vegetations in 03 cases. According to
the modified DUKE criteria, the diagnosis of endocarditis was retained in
27.30%. The evolution was marked by a high case fatality rate (45.45%). Conclusion: Endocarditis is an uncommon disease in children with a pulmonary portal of
entry and Staphylococcus aureus as
the main germ. Its mortality remains high.