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Zang, R., Case, J.B, Yutuc, E., Ma, X., Shen, S., Gomez Castro, M.F. Liu, Z., Zeng, Q., Zhao, H., Son, J., Rothlauf, P.W., Kreutzberger, A.J.B., Hou, G., Zhang, H., Sayantan, B., Wang, X., Vahey, M.D., Mani, K., Griffiths, W.J., Kirchhausen, T., Fremont, D.H., Guo, H., Diwan, A., Wang, Y., Diamond, M.S., Whelan, S.P.J. and Ding, S. (2020) Cholesterol 25-Hydroxylase Suppresses SARS-CoV-2 Replication by Blocking Membrane Fusion. Proceedings of the National Academy of Sciences of the United States of America, 117, 32105-32113.
https://doi.org/10.1073/pnas.2012197117

has been cited by the following article:

• TITLE: SARS-CoV-2 Infection Is Associated with Vitamin D Deficiency in Côte d’Ivoire

  AUTHORS: Lydie Boyvin, Yapi Guillaume Yayé, Gnogbo Alexis Bahi, Aya Jeanne Armande Aké, Kipré Laurent Séri, Daouda Sévédé, Serge Eholié, Mireille Dosso, Allico Joseph Djaman

  KEYWORDS: Côte d’Ivoire, SARS-CoV-2, Vitamin D Deficiency

  JOURNAL NAME: Advances in Microbiology, Vol.12 No.2, February 11, 2022

  ABSTRACT: In 2019, the coronavirus pandemic broke out as a serious public health issue worldwide. In Côte d’Ivoire, the number of cases of COVID-19 has increased rapidly. The Severe Acute Respiratory Syndrome virus (SARS-CoV-2) binds to angiotensin converting enzyme 2 (ACE2) receptors in the respiratory tracts and enters the respiratory and alveolar cells of infected patients. Deficiency of fat-soluble vitamin D3 is associated with respiratory distress syndrome and pulmonary fibrosis by activation of the renin-angiotensin system. In Côte d’Ivoire, very little research is being done on SARS-CoV-2 and vitamin D. The objective of this study was to assess the vitamin D status of people infected and suffering from COVID-19 in order to contribute to their medical treatment. The study involved 100 adults infected with SARS-CoV-2 (24 women and 76 men). After confirmation of the patient’s SARS-CoV-2 status by RT-PCR, the 25 (OH) vitamin D assay was performed on the Cobas 6000 device and compared to control subjects, the non-COVID-19 positive. A significant decrease in 25-hydroxy vitamin D3 concentrations (44 ± 1.29 nmole/L) was observed in patients infected with SARS-CoV-2, compared to control (78 ± 0.68 nmole/L) (p 3 deficiency requires vitamin D supplementation in the management of hospitalized patients infected with SARS-CoV-2.