TITLE:
Synthesis of Novel Virus-Like Mesoporous Silica-ZnO-Ag Nanoparticles and Quercetin Synergize with NIR Laser for Omicron Mutated Covid-19 Virus Infectious Diseases Treatment
AUTHORS:
Fadi Ibrahim
KEYWORDS:
Bacteriophage, Biomedical Applications, Covid-19, Omicron, Epitaxial Growth Zinc/Silica/Silver Nanoparticles, Infectious Diseases, NIR Laser, SEM/TEM, Photothermal, Quercetin, Virus-Like Mesopore
JOURNAL NAME:
Advances in Nanoparticles,
Vol.11 No.1,
February
10,
2022
ABSTRACT: This work shows that novel virus-like mesopore
silica-zinc oxide/Ag nanoparticles (SZnOAg) synthesized and professionally collected on NIR laser irradiation with
quercetin to improve the elimination the mutated virus as a biomedical
application. A unique type of silica nanoparticles with a self-in- flating tubular surface has been successfully
synthesized using a novel single-micelle epitaxial growth process. The
properties of the nanoparticles can be tuned with respect to their core
diameter, tubular length, and outer diameter. Due to their biomimetic
appearance, they can rapidly transform living cells into virus-like particles,
this SZnOAg nanomaterial has specific elimination effect on bacteriophage and Covid-19.
Using epitaxial growth, we can construct virus-like
structures that can be used for biomedicine applications. These nanomaterials
and NIR laser could open the way to a new range of antiviral materials, due to the low-efficiency cellular uptake of current
nanoparticles, their applications in the biomedical field are limited. Herein,
it clearly shows that novel mesoporous silica nanoparticles can be easily exhibited
superior cellular uptake property.