TITLE:
Study of the Impact of the Patient Rhythm during Cryoballoon Ablation on the Acute Biophysical Parameters
AUTHORS:
Mohamed Sanhoury, Gaetano Fassini, Salvatore Pala, Massimo Moltrasio, Fabrizio Tundo, Stefania Riva, Antonio Dello Russo, Michela Casella, Claudio Tondo
KEYWORDS:
Pulmonary Vein Isolation, Cryoballoon, Paroxysmal Atrial Fibrillation, Biophysical Parameters
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.12 No.1,
January
29,
2022
ABSTRACT: Background: Pulmonary vein isolation by means of cryoballoon is a well-established way of treatment of atrial fibrillation. The aim of the study was to compare the acute cryoballoon biophysical parameters attained during energyapplications to the individual pulmonary vein during sinus rhythm versusatrial fibrillation. Methods: 100 Patients who underwent their first-time PVI using second-generation cryoballoon for symptomatic and drug-refractory AF, between the beginning of March to end of August 2016, were initially screened.61 patients with paroxysmal AF were included in the present study. 39 patients with persistent AF were excluded. No pre-procedural anatomical imaging wasreported. Results: A total of 61 patients (male 80%, age 59.3 ± 13.4 years)were included in the present analysis. A total of 243 pulmonary veins were isolated with an average of 1.87 ± 1.14 cryo energy applications per individual vein. During cryo application, there were no significant differencesbetween applications delivered during sinus rhythm or ongoing AF in the rate of temperature drop at 5 and 30 s, rate of warming at 5 s after freezing stop orachieved balloon nadir temperature. The same also was observed for both the balloon cooling rate and warming times. Conclusions: The present analysis shows no impact of the patient baseline rhythm at the time of energy application uponthe acute balloon biophysical parameters in patients with normal sinusrhythmand those with ongoing atrial fibrillation using the second-generation cryoballoon.