TITLE:
Histological Analysis and Morphometric Changes after Autologous Fat Grafting in Large Volumes on Pigs
AUTHORS:
Hector Giancarlo Torres-Nuño, Walter Angel Trujillo-Rangel, Jorge Barrera-Alcocer, Miriam Méndez del Villar, Diana Mercedes Hernández-Corona, Sylvia Elena Totsuka-Sutto, Leonel García Benavides
KEYWORDS:
Autologous Fat Transfer, Adipose Tissue Transplant, Autologous Fat Injection, Gluteal Augmentation
JOURNAL NAME:
Journal of Cosmetics, Dermatological Sciences and Applications,
Vol.11 No.4,
December
30,
2021
ABSTRACT: Nowadays, fat transfer is an accepted technique that has been popularized in clinical practice, during which large volumes of fat are strategically relocated to increase and improve the contour of the body. In the present study, we investigated the histological and morphometric changes after large volumes of fat were grafted within the subcutaneous cellular tissue. An experimental study was designed using four 3-month-old male pigs. One hundred cc of decanted fat tissue was transferred into the right leg. Volume augmentation achieved by auto lipo-injecting within the subcutaneous cellular tissue persisted up to two months. Although there is a reduction in cell number and size, an increased amount of extracellular matrix and the presence of oily cysts and microcalcifications were observed. Conclusion: The volume augmentation, which is achieved by autologous fat transfer in large quantities in subcutaneous cellular tissue, can remain for months.