TITLE:
Risk Factors of Early Neonatal Deaths in Pediatric Teaching Hospital in Bangui, Central African Republic
AUTHORS:
Jean Chrysostome Gody, Moyen Engoba, Brice Olivier Bogning Mejiozem, Lydie Verleine Danebera, Evodie Pierrette Kakouguere, Marie Collette Nganda Bangue, Carine Judith Kiteze Nguinzanemou, Romuald Belly de Dieu Komangoya Kpembi, Petula Waraka, Dusie Lesly Ngoyoli Mbode, Mireille Mande Djapou, Ghislain Franck Houndjahoue, George Moyen
KEYWORDS:
Early Neonatal Mortality, Risk Factors, CHUPB, CAR
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.11 No.4,
December
30,
2021
ABSTRACT: Background: The neonatal mortality rate in the Central African Republic (CAR) is 42.3
per 1000 live births in 2017, indicating that CAR is with the highest number of
newborn deaths. Objective: The
objective is to clarify the risk factors of neonatal deaths in
this area. Methodology: A case-control study with retrospective data collection.
Targets were newborns >7 days, hospitalized and dead (cases), and newborns
admitted after the respective case during the study period and discharged
before the 7th day of life. This study was carried out between 2016
and 2018 in the neonatal unit of the “Complexe Hospitalier Universitaire
Pédiatrique de Bangui” (CHUPB), the only national hospital for newborns care in
the CAR. Results: We included 902 newborns, with 451 cases of early
neonatal death and 451 controls. 4168 newborns were admitted to the neonatology
unit with 621 early death cases; a lethality rate of 14.9%. Early neonatal
deaths factors were: newborns with low birth weight (OR = 22.59; 95% CI [15.93
- 32.04]; P 25 years
(OR = 2.08; 95% CI [1.58 - 2.73]; P 0.01); anoxo-ischemic encephalopathy (OR = 12.72; 95%
CI [6.54 - 34.73]; P 0.01);
delivery by cesarean section (OR = 0.59; 95% CI [0.41 - 0.84]; P Conclusion: The early neonatal mortality rate remains high in this area. Controlling the
factors mentioned above might lead to improving the survival of newborns.