TITLE:
Computed Tomography Evaluation of Tumor Response in Oncology in Togo
AUTHORS:
Abdoulatif Amadou, Pihou Gbande, Ablavi Adani-Ifè, Massaga Dagbe, Icael Youaleu, Lantam Sonhaye, Lama Kedigoma Agoda-Koussema, Komlanvi Adjenou
KEYWORDS:
Cancer, Response Tumoral, Computed Tomography, RECIST 1.1, Togo
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.12 No.12,
December
13,
2021
ABSTRACT: Cancer is common in our
setting and represents a real public health concern in sub-Saharan Africa. This
work aimed to assess the role of computed tomography in the follow-up of
patients treated for cancer in Togo. This was a retrospective descriptive study
carried out over a period of one year, on patients with cancer, treated in the
medical oncology unit of CHU Sylvanus Olympio and having undergone at
least two CT scans after cancer treatment. Computed tomography evaluation was
performed according to the RECIST 1.1 guidelines. We had found 46
patients. The mean age of the patients was 54.22 years with a female
predominance (sex ratio 1:2.5). Cancers mainly involved the urogenital system
(60.8%) followed by the digestive system (28.3%). Carcinoma represented 93.5%
of cases, mainly adenocarcinoma (45.7%). 74 target lesions were present at
baseline, with 18.9% and 11.6% disappearing at the first and second assessments
respectively. 36 non-target lesions were present at baseline, with 25% and
22.2% disappearing at the first and second assessments respectively. New
lesions were found in the abdominal region in 54.5% of cases and in the
thoracic region in 41.3% at the first and second assessments respectively.
58.7% of patients had a stable disease at the first assessment and 39.1% had
progression at the second assessment. 50% of them had received chemotherapy in
combination with surgery. Computed tomography using the RECIST 1.1 guidelines
is a necessity in monitoring tumor extensions and in the follow-up of cancer patients.