TITLE:
Gold Nanoparticles Incorporated with Cyclodextrins and Its Applications
AUTHORS:
Fahad Abdulaziz, Dina Salah
KEYWORDS:
Gold Nanoparticles, Cyclodextrins, Sensors, Antimicrobe, Biomedicine
JOURNAL NAME:
Journal of Biomaterials and Nanobiotechnology,
Vol.12 No.4,
October
29,
2021
ABSTRACT: Cyclodextrins are naturally oligosaccharides which had cyclic glucopyranoside units even if six units to form α-cyclodextrin (α-CD), seven units β-cyclodextrin (β-CD) or eight units γ-cyclodextrin (γ-CD) and some other derivatives. It has a truncated cone shape with a hydrophobic cavity and a hydrophilic from the external surface of cyclodextrins. Gold nanoparticles incorporated with cyclodextrins enhanced optical and electrical properties of the resulting conjugates, due to the gold nanoparticles’ unique physical and chemical properties because of their surface plasmon resonance. Here is a review of gold nanoparticles/cyclodextrin’s different applications including sensing, antimicrobial effect, and their variable medical/pharmaceutical applications. Generally, gold nanoparticles and cyclodextrin conjugates showed developed and pronounced advantages due to their biocompatibility and enhanced physical and electric properties.