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Oscar, F.L., Vismaya, S., Arunkumar, M., Thajuddin, N., Dhanasekaran, D. and Nithya, C. (2016) Algal Nanoparticles: Synthesis and Biotechnological Potential. In: Thajuddin, N. and Dhanasekaran, D., Eds., Algae, IntechOpen, Rijeka, Chapter 7.

has been cited by the following article:

• TITLE: Gold Nanoparticles: Synthesis and Effect on Viability of Human Non-Small Lung Cancer Cells

  AUTHORS: Rakesh Sharma, Yuvraj Singh Negi

  KEYWORDS: Brown Algae, Undaria sp., Gold Nanoparticles, MTT Assay, Non-Small Lung Cancer Cells

  JOURNAL NAME: Advances in Materials Physics and Chemistry, Vol.11 No.9, September 30, 2021

  ABSTRACT: Gold nanoparticles recently showed great interest for many uses including food, drug and medical applications. The algaeUndariasp.well known as wakame in South Asia are considered to be large edible brown algae. It provides nutritious source of dietary fiber, vitamin Bs and mineral. The present study aimed to investigate the use ofUndariasp.for green synthesis of metallic gold nanoparticles. The synthesized nanoparticles were characterized for physicochemical properties including size measurement and testedinvitrofor their effect on viability of human non-small lung cancer H-460 cell line using the MTT assay. From the results, brown algae were able to chemically form nanoparticles with chloroauric acid solution possibly due to the sulphated polysaccharides found in algae. The particle sizes were found to be approximately 10 nm. The gold nanoparticles stabilized by the algae could decrease the cancer cell viability. However, the properties and biological activity of nanoparticles seemed to depend upon reaction time and temperature. Conclusively, gold nanoparticles synthesized and stabilized by the algae could decrease the cancer cell viability, thus indicating the potential of such nanoparticles for further study for anticancer activity.