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Vijay, S., Natalie, R.H., Nilesh, M.M., Sharon, Y.I., Sarah, B.K., Hchristine, A., Katri, V.T., Natalie, Z.C., Vincent, S.F., David, W., et al. (2020) Early Enteral Nutrition Is Associated with Improved Clinical Outcomes in Critically Ill Children: A Secondary Analysis of Nutrition Support in the Heart and Lung Failure-Pediatric Insulin Titration Trial. Pediatric Critical Care Medicine, 21, 213-221.
https://doi.org/10.1097/PCC.0000000000002135

has been cited by the following article:

• TITLE: Application of Early Enteral Nutrition in Critically Ill Children

  AUTHORS: Musheng Li, Lini Chen

  KEYWORDS: Early Enteral Nutrition, Childhood, Critical Care, Intensive Care Unit

  JOURNAL NAME: Open Journal of Pediatrics, Vol.11 No.4, September 30, 2021

  ABSTRACT: Objective: The objective is to investigate the incidence of moderate and severe malnutrition in children in intensive care units, and to analyze the safety and clinical efficacy of early enteral nutrition therapy in critically ill children. Methods: A total of 80 children hospitalized in the pediatric care unit meeting the inclusion criteria were selected and general data were collected, including 48 in the early enteral nutrition (EEN) group and 32 in the late EN group. The two groups were compared in the incidence of moderate to severe malnutrition, feeding tolerance, length of stay in ICU, total length of stay, changes in blood routine and biochemical indicators. Results: After 1 week in ICU, the feeding tolerance of the treatment group was better than that of the control group (P 0.01). After 1 week of treatment in ICU, serum prealbumin in treatment group was significantly higher than that in control group (P albumin was not significantly higher (P > 0.05). The rate of moderate to severe malnutrition at discharge was lower in the treatment group than at admission to the ICU (17 cases vs. 20 cases, 35.4% vs. 41.7%), but higher in the control group (19 cases vs. 16 cases, 59.4% vs. 50.0%). Conclusion: Malnutrition is prevalent in children treated in pediatric intensive care units. Early enteral nutrition therapy for critically ill children is safe and effective, that can significantly improve the nutritional status of critically ill children, reduce inflammatory response, and shorten the hospital stay.