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Bernal, J. L., Andrews, N., Gower, C., Gallagher, E., Simmons, R., Thelwall, S., Stowe, J., Tessier, E., Groves, N., Dabrera, G., Myers, R., Campbell, C., Amirthalingam, G., Edmunds, M., Zambon, M., Brown, K., Hopkins, S., Chand, M., & Ramsay, M. (2021). Effectiveness of COVID-19 Vaccines against the B.1.617.2 Variant. BMJ.
https://doi.org/10.1101/2021.05.22.21257658

has been cited by the following article:

• TITLE: Practical Mitigation Strategies for Countering the Spread of Aerosolized COVID-19 Virus (SARS-CoV-2) Using Ventilation and HEPA Air Purifiers: A Literature Review

  AUTHORS: Panayiotis Polyzois, Shirley Thompson

  KEYWORDS: COVID-19, SAS-CoV-2, Aerosolized, Ventilation, HEPA Air Purifier(s)

  JOURNAL NAME: Journal of Geoscience and Environment Protection, Vol.9 No.9, September 29, 2021

  ABSTRACT: This paper assesses, through an extensive literature review, the use of ventilation and High-Efficiency Particulate Air (HEPA) purifiers as practical mitigation strategies for reducing the spread of aerosolized COVID-191 virus. HEPA is a well-defined standard by the U.S. Department of Energy for filters. The focus of the literature review was on indoor air quality (IAQ) and COVID-19, with a particular emphasis on classroom settings. The start of the review, January 2020, was chosen to coincide with the first cases of COVID-19 in North America. Although children under the age of 12 are currently not yet vaccinated, there is mounting pressure for a return to normal by the start of the new school year, 2021. Also, many classrooms lack pre-installed mechanical ventilation systems (Olsiewski et al., 2021); therefore, mitigation in classrooms often falls solely in the hands of teachers and students. Research shows that ventilation and air purification are essential tools to counter aerosolized transmission (Curtius et al. (2020), the inhaled dose of particles containing virus RNA is six times lower when using air purifiers with an ACH (air changes per hour) of 5.7. However, ventilation and air purifiers are not replacements for masks, which remain vital for countering droplet (>5 μm) transmission. In addition, occupancy (i.e., number and proximity of people present in a given area) and group activity levels (e.g., talking, shouting, singing) play a critical role in viral transmission. Although natural ventilation by opening windows can be an essential strategy to help counter the spread of the virus, the level of ventilation offered by opening windows is largely uncontrollable as it is subject to weather conditions and building design. One must also consider the energy implications (i.e., loss of heat) that this strategy carries. Scientific evidence shows that varying levels of continuous and/or intermittent ventilation, either mechanical or natural, combined with the use of HEPA air purifiers, can provide a higher degree of protection than window access alone (Curtius et al., 2020). Systematic deployment of a hybrid mitigation strategy incorporating both ventilation and HEPA air purification in schools, offices, or other facilities offers a practical way to establish a safe re-opening of society in Canada.