TITLE:
Does Caffeine Citrate Administration Decrease Risk of Acute Kidney Injury in Hospitalized Preterm Neonates?
AUTHORS:
Fatma H. Mohamed, Saneya A. Fahmy, Amal G. Mohamed
KEYWORDS:
Caffeine Citrate, Acute Kidney Injury, Neonates
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.11 No.3,
September
29,
2021
ABSTRACT: Background: Acute kidney injury (AKI) is a life threatening
condition with still high mortality rate in neonates. Early recognition of the
risk factors and the rapid effective treatment of the contributing conditions
will reduce AKI in the neonatal period. Aim of the Work: To determine association between early
caffeine citrate administration and risk of acute kidney injury in hospitalized
preterm neonates.Patients and Methods: This study was a prospective study that was conducted at
the NICU of El Galaa Teaching Hospital. This study included 100 preterm
neonates who were born alive from 32 weeks to 35 weeks of gestation. Results: There was highly
statistically significant occurrence of apneaic episode in preterm babies who
don’t receive caffeine citrate and consequently decreased incidence of AKI in
those babies. Conclusion: We concluded that caffeine citrate administration in
preterm babies is associated with reduced incidence of apneaic episode and
consequently reduced risk of AKI.