TITLE:
Electrophoresis of Proteins in the Biochemistry Laboratory of the University Hospital of Brazzaville
AUTHORS:
Fylla Koumou Onanga, Jeanne Kibah Gambomi, Monde Ikia, Rod Ibara-Okabande, Barnes Yoyo, C. R. Dobhat-Doukakini, Reine F. Eboka-Loumingou Sakou, Childerick Lekana, Aliocha Natuhoyila Nkodila, Etienne Mokondjimobé, Benjamin Longo Mbenza
KEYWORDS:
Electrophoresis, Serum Proteins, Minicap, Protein Profiles
JOURNAL NAME:
Open Access Library Journal,
Vol.8 No.9,
September
18,
2021
ABSTRACT: Background and aim: The electrophoresis of serum proteins is one of the examinations requested at the Biochemistry laboratory, with a view to highlight various pathologies. The aim of our study is to analyze the different electrophoretic profiles encountered in our current practice. Methods: This is a retrospective study of 350 serum samples collected at the biochemistry laboratory of the University Hospital Center (CHU) of Brazzaville. The electrophoresis of serum proteins was carried out on a Minicap Flex Piercing machine from Sebia. Results: One hundred and ninety-five (195) sera from women and 155 sera from men were collected from patients aged 12 to 85 years. Ninety-one, or 26% of PSE were normal. Two hundred and fifty nine or 74% were pathological. Inflammation was noted in 194 (55%) of cases of which 145 (41%) were chronic and 49 (14%) acute. Forty-two (12%) of our patients had beta-gamma block and 11 (3%) others presented with nephrotic syndrome. Monoclonal peaks were observed in 12 patients (3%). Conclusion: This study highlights the plurality of different electrophoretic profiles, with a predominance of profiles emanating from the Gastro-Enterology department. It nevertheless reveals the question of relevance in the request for these examinations, since no clinical information is documented for the attention of the clinical practitioner.