TITLE:
Management and Development of Newborns from Mothers Carrying HBsAg at the El Rapha Polyclinic in Libreville, Gabon
AUTHORS:
Eliane Kuissi Kamgaing, Steeve Minto’o Rogombe, Aude-Mariella Lembet Mikolo, Raïssa Koumba Maniaga, Edmée Mintsa Mi Nkama, Edgar-Brice Ngoungou, Maiga, Aité, Blaise Okissi, Marcelle Djiomo, Simon Ategbo
KEYWORDS:
Viral Hepatitis B, Newborn, Management, Evolution, Gabon
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.11 No.3,
September
15,
2021
ABSTRACT: Introduction: Hepatitis B is a significant public health problem.
Infected children Objective: We aimed to assess newborns’ management and
outcome from reactive HBs Ag mothers at the El Rapha Polyclinic in Libreville,
Gabon. Methodology: Prospective longitudinal study, carried out over
four years, including all neonates born from reactive HBsAg mothers admitted in
the delivery room. The parameters studied were maternal age, gestation, marital
status, pregnancy follow-up, hepatitis B vaccination status, knowledge of
hepatitis B, anti-Hbc antibodies’ levels, HBeAg. For the newborn: term, birth
weight, management at birth, and hepatitis B serological status at 12 months. Results: We included 45 newborns. Mothers’ mean age was 30.9 ± seven years.
In 32.6% of cases, antenatal consultations were ≤4, and 9.3% were vaccinated
for hepatitis B. Mothers had chronic hepatitis in 74.4% of cases. All neonates
were vaccinated for hepatitis B at birth; 68.9% received hepatitis B
immunoglobulin. At 12 months, 77.8% had HBs antibody positive, and 6.7% were
HBsAg positive. Conclusion: Hepatitis B prevalence is significant among
parturients. It is essential to set up a national strategy for managing the
mother-child couple in a context of positive HBsAg.