TITLE:
Effect of Adding a Delayed Blastocyst to a Good Quality One during Embryo Transfer on ICSI Cycle Outcomes
AUTHORS:
Mohamed Elmahdy, Emadeldin Khalifa, Passant Radwan, Yasser Elkassar
KEYWORDS:
Embryo Transfer, ICSI, Delayed Blastocyst, Pregnancy Rate
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.11 No.8,
August
25,
2021
ABSTRACT: Objectives: Study the effect of adding a delayed blastocyst to a
transferred good quality one on ICSI cycle outcomes. Study design: Prospective cohort
study. Participants/materials, setting, methods: 90 infertile patients aged
from 20 - 35 years due to mild male factor, unexplained infertility or tubal
factor. Patients with PCOS, endometriosis, RIF, poor responder and azoospermia
were excluded. Setting: Duration 6 months from October
2019 to April 2020 in a private IVF center in Egypt. 30 cases were
subjected to elective single embryo transfer and the other 60 with two embryo
transfers, one good quality and another
poor quality blastocyst. Results: (clinical pregnancy rate) was comparable
between the two groups, being 47.7% and 36.7% in SET and DET groups
respectively (p = 0.361). Miscarriage and ectopic pregnancy rate were observed
in 10% of the cases pregnant after SET (group I) and in only 6.7% of the cases
pregnant after DET (group II) denoting no significant statistical difference
between the two groups. The highest incidence was missed miscarriages in the
two groups and ectopic pregnancy was observed only in one case in group II
(DET). Twin pregnancy occurred in 22% of pregnant females in the second group.
Late pregnancy complications in the form of preterm labour, premature rupture
of membrane and preeclampsia occurred mainly in pregnant females in the second
group 18%. Conclusion: Neither adding a delayed blastocyst negatively affected the good
one nor affected the live birth rate but increased multiple pregnancy rates.