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Alvim, H.G.O., Correa, J.R., Assumpcao, J.A.F., da Silva, W.A., Rodrigues, M.O., de Macedo, J.L., Fioramonte, M., Gozzo, F.C., Gatto, C.C. and Neto, B.A.D. (2018) Heteropolyacid-Containing Ionic Liquid-Catalyzed Multicomponent Synthesis of Bridgehead Nitrogen Heterocycles: Mechanisms and Mitochondrial Staining. The Journal of Organic Chemistry, 83, 4044-4053.
https://doi.org/10.1021/acs.joc.8b00472

has been cited by the following article:

• TITLE: Bismuth (III) Chloride Catalyzed Multicomponent Synthesis of Substituted Hexahydroimidazo[1, 2-a]Pyridines

  AUTHORS: Noah T. Haskin, Richard A. Guingrich, Allison J. Schrader, Matthew R. Crosse, Alpa Y. Dave, Eeshwaraiah Begari, Ram S. Mohan

  KEYWORDS: Bismuth Chloride, Green Chemistry, Heterocycles, Multicomponent Reactions

  JOURNAL NAME: Green and Sustainable Chemistry, Vol.11 No.3, August 5, 2021

  ABSTRACT: The synthesis of nitrogen containing heterocycles is of particular interest in the pharmaceutical industry due to the range of biological activities exhibited by such compounds. Their synthesis using multicomponent reactions saves steps and minimizes waste generation. The bismuth (III) chloride multicomponent synthesis of a series of hexahydroimidazo[1, 2-a]pyridines is reported. Bismuth (III) compounds are especially attractive from a green chemistry perspective because they are remarkably nontoxic, non-corrosive and relatively inexpensive. The reported method avoids chromatography and an aqueous waste stream to afford the products in a very mass efficient manner.