TITLE:
Comparative Study between Shortened versus Standard Protocols of Postpartum Magnesium Sulphate Regimen in the Treatment of Eclampsia
AUTHORS:
Nermeen Mohamed Hefila, Tamer Mamdouh Abdeldayem
KEYWORDS:
MgSO4, Eclampsia, MgSO4 Protocols
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.11 No.8,
August
3,
2021
ABSTRACT: Eclampsia
is one of the most sever, life-threatening diseases occurred in pregnancy, MgSO4 is the best drug used for its treatment. In this study, the comparison between shortened regimen of MgSO4 versus standard Zuspan course in controlling eclampsia was done. This study performed along one year
(July 2019-July 2020) at El Shatby Maternity University Hospital, 40 eclamptic
patients presenting at the emergency unit were randomized. Group A received the
standard Zuspan regimen of magnesium sulphate and group B received short course in which the patients received only two doses of intravenous
magnesium sulphate four hours apart postpartal. Results: The maternal outcomes regarding
recurrence of the fits were compared. The maternal complications and postpartal fits were the same in both
groups. The dose of MgSO4 in the shortened group was decreased by
40% in 42.5% of the cases. Conclusions: The shortened course of MgSO4 postpartal is the same as the standard regimen
in the controlling eclampsia.