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Frota Filho, J.D., Drews, C., Leães, P., Blacher, C., Tostes, F., Delatorre, N., Vieira, M., Lúcio, E., Pereire, W., Sales, M., Lobo, R., Stuermer, R., Tanaka, N., Portugal, L. and Luchese, F. (2001) Postoperative Necrotizing Fasciitis of the Thorax in Cardiac Surgery. Arquivos Brasileiros de Cardiologia, 76, 250-254.
https://doi.org/10.1590/S0066-782X2001000300008

has been cited by the following article:

• TITLE: Necrotizing Soft Tissue Infections of the Male and Female Breast: A Literature Review

  AUTHORS: Areta Kowal-Vern, Daniela Cocco, Marc R. Matthews

  KEYWORDS: Breast, Necrotizing Fasciitis, Necrotizing Soft Tissue Infections, Chest Wall, Gangrene

  JOURNAL NAME: Surgical Science, Vol.12 No.7, July 28, 2021

  ABSTRACT: Background: Within the spectrum of necrotizing soft tissue infections (NSTI), necrotizing fasciitis (NF) has been characterized by tissue and fascial necrosis with systemic toxicity. The objective was to determine and summarize the frequency and characteristics of breast NF and NSTI in the literature. Methods: Cases were obtained through PubMed, Google Scholar, Google, and from published article reference sections. One hundred twenty-three cases were gleaned from 96 articles that reported NF and NSTI of the breast (1924 through 2021). Results: NF was reported in 70 and NSTI in 53 cases (111 women and 12 men). Patients presented with swollen, painful breasts, erythema, bullae, crepitus, necrosis, gangrene, fever, tachycardia, and neutrophilia. Fifty-nine of 123 (48.4%) patients were septic on admission. The most frequent microorganisms were β hemolytic Group A Streptococcus, and Staphylococcus aureus. Treatment consisted of antibiotics, mastectomy and debridement with flaps, skin grafts or primary and secondary closure. Forty-four (63.0%) of the NF cases had chest wall involvement; of these, 18 (14.6%) involved the breast secondarily, P P = 0.007. Conclusions: Men and women with breast NF and NSTI presented with similar signs and symptoms and required the same emergent treatment as provided for NF and NSTI of the more common sites. As a time-sensitive disease, patients treated within 12 hours of admission had a better survival. Patients with NF were more likely to have sepsis on admission, a higher mortality, and fascial chest wall/muscle involvement than patients with NSTI.