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Breugom, A.J., van Gijn, W., Muller, E.W., Berglund, Å., van den Broek, C.B., Fokstuen, T., Gelderblom, H., et al. (2015) Adjuvant Chemotherapy for Rectal Cancer Patients Treated with Preoperative (Chemo)radiotherapy and Total Mesorectal Excision: A Dutch Colorectal Cancer Group (DCCG) Randomized Phase III Trial. Annals of Oncology: Official Journal of the European Society for Medical Oncology, 26, 696-701.
https://doi.org/10.1093/annonc/mdu560

has been cited by the following article:

• TITLE: Five Year Survival Outcomes of Prospectively Recorded Cohort Data for Older Adults versus Younger Adults with Resected Primary Rectal Cancer

  AUTHORS: Mohsen Shafiei, Philip Beale, Prunella Blinman

  KEYWORDS: Rectal Cancer, Chemotherapy, Radiotherapy, Overall Survival, Cancer Specific Survival

  JOURNAL NAME: Journal of Cancer Therapy, Vol.12 No.7, July 22, 2021

  ABSTRACT: Background: Rectal cancer predominantly occurs in older adults. We aimed to compare the long-term outcomes of older adults (≥70 years) versus younger adults (Methods: Consecutive patients who had resection of a primary rectal cancer between January 1, 2000 and December 31, 2010 were identified from a prospective database at the Concord Repatriation General Hospital and stratified into two age groups: ences in patients, cancer, and treatment characteristics were determined by Chi-square tests. 5-year Overall Survival (OS) and Cancer-Specific Survival (CSS) were determined by the Kaplan-Meier method and by multivariable Cox regression analysis. Results: Of 714 included patients, the mean age was 65.8 years (range, 21 - 92 years). 407 (57%) patients were aged 70 years. Older age (>70 years) predicted more comorbidity (p 70 years), compared with younger adults (Conclusion: Older adults who had had a resection of stage I-IV primary rectal cancer received less neoadjuvant and adjuvant therapy and had worse OS and CSS than their younger counterparts.