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Shen, Y.M., Lv, P.C., Chen, W., Liu, P.G., Zhang, M.Z. and Zhu, H.L. (2010) Synthesis and Antiproliferative Activity of Indolizine Derivatives Incorporating a Cyclopropylcarbonyl Group against Hep-G2 Cancer Cell Line. European Journal of Medicinal Chemistry, 45, 3184-3190.
https://doi.org/10.1016/j.ejmech.2010.02.056
has been cited by the following article:
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TITLE:
Novel Tandem Three Consecutive Reactions: Aza-Wittig, Imine Condensation and Electrophilic Aromatic Substitution Strategy to Indolizine Synthesis
AUTHORS:
Julio C. González-Rodríguez, Carlos González-Romero, Erick Cuevas-Yáñez, Juan J. Mejía Vega, Christopher K. Jankowski, David Corona-Becerril
KEYWORDS:
Iminophosphorane, Tandem Reaction, Indolizine Synthesis
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.11 No.2,
June
30,
2021
ABSTRACT: Reaction of ethyl
(Z)-3-(heteroaryl/aryl)-2-((triphenyl-λ5-phosphaneylidene) amino) acrylates
intermediates with 2,3-thiophenedicarboxaldehyde
was used in novel Tandem three
consecutive reactions: aza-Wittig, imine condensation and electrophilic heteroaromatic cyclization to obtain a series of
indolizines. A tentative mechanism of this reaction is proposed.