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Leeson, P.D. and Springthorpe, B. (2007) Experimental and Computational Approaches to Estimate Solubility and Permeability in Drug Discovery and Development Settings. Nature Reviews Drug Discovery, 6, 881-890.
https://doi.org/10.1038/nrd2445

has been cited by the following article:

• TITLE: Novel Tandem Three Consecutive Reactions: Aza-Wittig, Imine Condensation and Electrophilic Aromatic Substitution Strategy to Indolizine Synthesis

  AUTHORS: Julio C. González-Rodríguez, Carlos González-Romero, Erick Cuevas-Yáñez, Juan J. Mejía Vega, Christopher K. Jankowski, David Corona-Becerril

  KEYWORDS: Iminophosphorane, Tandem Reaction, Indolizine Synthesis

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.11 No.2, June 30, 2021

  ABSTRACT: Reaction of ethyl (Z)-3-(heteroaryl/aryl)-2-((triphenyl-λ5-phosphaneylidene) amino) acrylates intermediates with 2,3-thiophenedicarboxaldehyde was used in novel Tandem three consecutive reactions: aza-Wittig, imine condensation and electrophilic heteroaromatic cyclization to obtain a series of indolizines. A tentative mechanism of this reaction is proposed.