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W. C. Reeves, J. J. Jones, E. Maloney, C. Heim, D. C. Hoaglin, R. Boneva, et al., “New Study on the Prevalence of CFS in Metro, Urban and Rural Georgia Populations,” Population Health Metrics, Vol. 5, 2007. http:// www.pophealthmetrics.com/content/5/1/5

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• TITLE: Sensitivity and Specificity of the CDC Empirical Chronic Fatigue Syndrome Case Definition

  AUTHORS: Leonard A. Jason, Meredyth Evans, Abigail Brown, Molly Brown, Nicole Porter, Jessica Hunnell, Valerie Anderson, Athena Lerch

  KEYWORDS: Chronic Fatigue Syndrome, Empirical Case Definition, Centers for Disease Control and Prevention, Fukuda Criteria

  JOURNAL NAME: Psychology, Vol.1 No.1, April 29, 2010

  ABSTRACT: In an effort to bring more standardization to the chronic fatigue syndrome (CFS) Fukuda et al. case definition [1], the Centers for Disease Control and Prevention (CDC) has developed an empirical case definition [2] that specifies crite-ria and instruments to diagnose CFS. The present study investigated the sensitivity and specificity of this CFS em-pirical case definition with diagnosed individuals with CFS from a community based study that were compared to non-CFS cases. All participants completed questionnaires measuring disability (Medical Outcome Survey Short-Form-36) [3], fatigue (the Multidimensional Fatigue Inventory) [4], and symptoms (CDC Symptom Inventory) [5]. Findings of the present study indicated sensitivity and specificity problems with the CDC empirical CFS case defi-nition.