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A. L. Stewart, S. Greenfield, R. D. Hayes, K. Wells, W. H. Rogers, S. D. Berry, et al., “Functional Status and Well-Being of Patients with Chronic Conditions: Results from the Medical Outcomes Study,” Journal of the American Medical Association, Vol. 262, No. 7, 1989, pp. 907-913.

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• TITLE: Sensitivity and Specificity of the CDC Empirical Chronic Fatigue Syndrome Case Definition

  AUTHORS: Leonard A. Jason, Meredyth Evans, Abigail Brown, Molly Brown, Nicole Porter, Jessica Hunnell, Valerie Anderson, Athena Lerch

  KEYWORDS: Chronic Fatigue Syndrome, Empirical Case Definition, Centers for Disease Control and Prevention, Fukuda Criteria

  JOURNAL NAME: Psychology, Vol.1 No.1, April 29, 2010

  ABSTRACT: In an effort to bring more standardization to the chronic fatigue syndrome (CFS) Fukuda et al. case definition [1], the Centers for Disease Control and Prevention (CDC) has developed an empirical case definition [2] that specifies crite-ria and instruments to diagnose CFS. The present study investigated the sensitivity and specificity of this CFS em-pirical case definition with diagnosed individuals with CFS from a community based study that were compared to non-CFS cases. All participants completed questionnaires measuring disability (Medical Outcome Survey Short-Form-36) [3], fatigue (the Multidimensional Fatigue Inventory) [4], and symptoms (CDC Symptom Inventory) [5]. Findings of the present study indicated sensitivity and specificity problems with the CDC empirical CFS case defi-nition.