TITLE:
Joint Effects of Mexidol and Nitroglycerine on Nitric Oxide Formation in Animal Liver Tissues
AUTHORS:
Taasilkan Zhumabaeva, Zoya Kuropteva, Zhoomart Moldaliev, Nazgul Zhumabaeva, Amanai Kadyrbaeva, Nurbek Bopoev, Zhypargul Abdullaeva
KEYWORDS:
Nitroglycerine, Liver Tissue, Nitric Oxide, Mexidol, Joint Effect, EPR Spectra
JOURNAL NAME:
American Journal of Molecular Biology,
Vol.11 No.3,
June
22,
2021
ABSTRACT: This work is investigating Mexidol (2-ethyl-6-methyl-3-hydroxy pyridine succinate) effect on the formation of nitric oxide (NO) in animal liver tissues, which is a regulator of many physiological processes and plays an important role in the vascular relaxation, neurotransmission and immune system functioning. Analyses performed by EPR spectroscopy revealed Hem-NO complex signals from paramagnetic centers in arbitrary units; produced nitrogen oxide amount in liver tissues was determined by method of double integration signals from nitrosyl complexes.