TITLE:
Case Report: The Paratesticular Rhabdomyosarcoma in Children
AUTHORS:
Manal Azizi, Abdeladim Babakhouya, Maria Rkain, Noufissa Benajiba
KEYWORDS:
Rhabdomyosarcoma, Tumor Paratesticular, Treatment
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.12 No.6,
June
11,
2021
ABSTRACT: Rhabdomyosarcoma is a rare and aggressive mesenchymal tumor, whose
paratesticular location is the most common genitourinary site. It is the
prerogative of the child and the young adult.
On physical examination, a painless scrotal tumefaction is observed. His
diagnosis is essentially provided by testicular ultrasound. His therapeutic
strategy is codified and based on the combination of chemotherapy and surgical
excision or radiotherapy. The precocity of the management and the
accuracy of the extension and radiology tests are important for the vital and
functional prognosis. We report a case of paratesticular rhabdomysarcoma of
alveolar type, diagnosed in front of a large left painless scrotal mass, which
has been evolving for less than one month in a 7-year-old
child. An inguinal orchiectomy was performed. A histological examination of the
excised tissue revealed an epididymal RMS of the alveolar type. Our patient had
9 chemotherapy sessions with vincristine, actinomycin C and cyclophosphamide.
Each chemotherapy session took place over four days, with a 21-day cycle. He was evaluated for 4 years and demonstrated good clinical improvement. The experience
gained from the index case is crucial for the management of patients
with intratesticular rhabdomyosarcoma who must always ensure that the radical
inguinal orchiectomy with lymph node dissection is covered by chemotherapy
and/or radiotherapy. This will potentially
reduce the chances of tumor recurrence and/or metastasis, thus improving
patient prognosis.