Article citationsMore>>

de Carlo, T.E., Chin, A.T., Bonini Filho, M.A., Adhi, M., Branchini, L., Salz, D.A., et al. (2015) Detection of Microvascular Changes in Eyes of Patients with Diabetes but Not Clinical Diabetic Retinopathy Using Optical Coherence Tomography Angiography. Retina, 35, 2364-2370. https://doi.org/10.1097/IAE.0000000000000882

has been cited by the following article:

• TITLE: Obese Foveal Avascular Zone Assessed by Optical Coherence Tomography Angiography of the Retina: Is There a Relation to Comorbities?

  AUTHORS: Jamilla Viana Silva Asfora, Márcio Bittar Nehemy, Diego Nery Benevides Gadelha, Carlos Teixeira Brandt

  KEYWORDS: Obesity, Retina, Fovea Centralis, Retinal Vessels, Optical Coherence Tomography Angiography

  JOURNAL NAME: Open Journal of Ophthalmology, Vol.11 No.2, May 31, 2021

  ABSTRACT: Purpose: To investigate the foveal avascular zone (FAZ) in obese by optical coherence tomography angiography (OCT-A) and to evaluate the findings of structural optical coherence tomography (OCT) and their relations with comorbidities. Methods: It was included 35 obese (study group) and 30 normal individuals (control group). Patients with retinal diseases and retinal treatments were excluded. The images were obtained using the Topcon®;. Results: The mean areas of FAZ in superficial plexus (FAZ-SP) and deep plexus (FAZ-DP) were significantly greater in the study group: FAZ-SP was 405.0 ± 136.4 μm2 in the obese group and 307.3 ± 78.6 μm2 in the control group and in the left eye (LE) 477.1 ± 124.4 μm2 in the obese group and 384.0 ± 88.7 μm2 in the control group. This difference was statistically significant (RE: p = 0.0014 and LE: p = 0.0012). The mean area of the FAZ-DP was 491.0 ± 124.4 μm2 (Right eye—RE) in the obese group and 384.4 ± 88.7 μm2 in the control group and in the left eye (LE) was 497.9 ± 124.1 μm2 in the obese group and 484.9 ± 92.7 μm2 in the control group. There were no correlations regarding FAZ-SP and FAZ-DP in both eyes with fasting blood glucose, glycated hemoglobin, total cholesterol and fractions and triglycerides. A significant association between enlargement of FAZ-DP and type 2 diabetes mellitus (p = 0.0160) was observed. Conclusion: The FAZ areas in superficial and deep plexus achieved significantly greater values in the study group. There was a significant association between a larger deep FAZ area and type 2 diabetes mellitus. It is necessary an evaluation with a larger sample size to corroborate the findings.