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Sorsa, T., Tervahartiala, T., Leppilahti, J., Hernandez, M., Gamonal, J., Tuomainen, A.M., Lauhio, A., Pussinen, P.J. and Mantyla, P. (2011) Collagenase-2 (MMP-8) as a Point-of-Care Biomarker in Periodontitis and Cardiovascular Diseases. Pharmacological Research, 63, 108-113.
https://doi.org/10.1016/j.phrs.2010.10.005

has been cited by the following article:

• TITLE: Impact of Non-Surgical Periodontal Therapy on the Salivary Levels of Tissue Inhibitor of Metalloproteinse-1 (TIMP-1) in Patients with Chronic Periodontitis: A Third World Experience

  AUTHORS: Abimbola Olubunmi Balogun, Juliana Obontu Taiwo, Olanrewaju Ige Opeodu, Bukola Folashade Adeyemi, Bamidele M. Kolude

  KEYWORDS: TIMP-1, Periodontal Treatment, Saliva, ELIZA

  JOURNAL NAME: Open Journal of Stomatology, Vol.11 No.5, May 20, 2021

  ABSTRACT: Chronic periodontitis is a disease of public health concern due to its high prevalence globally, especially in the elderly. The aim of this study was to determine the impact of non-surgical periodontal therapy on salivary levels of TIMP-1 among patients with chronic periodontitis in Nigeria. In this experimental study, unstimulated whole saliva (2 mL) was collected from participants in the experimental and control groups, coded (SP1-40 and SH1-40) respectively and assays for salivary TIMP-1as well as clinical measurements such as plaque (PI), probing depths (PD), and CAL were recorded before and 4 weeks after periodontal treatment. Assay was done using Quantikine human TIMP-1 ELISA kit. Data were presented using frequency tables, means and standard deviation. Paired-T Test assessed association between salivary TIMP-1 before and after treatment. Pearson correlation coefficient was used to correlate salivary TIMP-1 levels with clinical parameters of periodontal disease and levels of statistical significance were set at p