TITLE:
Secondary Hypertrophic Osteoarthropathy or Pierre-Marie Syndrome Bamberger: Clinical Case and Literature Review
AUTHORS:
Kaba Condé, Carlos Othon Guelngar, Awada Mohamed, Igué Kadidjatou, Douna Granga Daouya, Mamadou Ciré Barry, Mamadou Hady Diallo, Karinka Diawara, Konaté Mamady, Touré Moriba, Fodé Abass Cissé
KEYWORDS:
Hypertrophic Osteoarthropathy, Pulmonary Adenocarcinoma, Guinea
JOURNAL NAME:
Open Journal of Rheumatology and Autoimmune Diseases,
Vol.11 No.2,
May
20,
2021
ABSTRACT: Secondary hypertrophic osteoarthropathy, or Pierre-Marie Bamberger syndrome, is characterized by the association of digital clubbing, polyarthritis and periostitis affecting the long bones. Most commonly it is a paraneoplastic syndrome associated with lung cancer in 80% of cases. We report the case of a 49-year-old female patient who is actively smoking, one pack per day for 20 years. Seen in consultation for pain and swelling of the hands, elbows, knees, ankles, and feet evolving for about 5 months, associated with a poorly differentiated pulmonary adenocarcinoma. On history, she told us about a weight loss of about 8 kg, no fever, no cough, no family history of inflammatory rheumatism or cancer. Bilateral digital clubbing was noted. The diagnosis was based on imaging and histology. Treatment with nonsteroidal anti-inflammatory drugs (NSAIDs) and chemo-radiotherapy was started.