TITLE:
Neuropathophysiology of COVID-19
AUTHORS:
I. Abi, E. Iwuozo, E. Abi, J. R. Ediale
KEYWORDS:
COVID-19, SARS-CoV-2, Charnoly Body, Cytokine Storm, Agnosia, Ageusia
JOURNAL NAME:
World Journal of Neuroscience,
Vol.11 No.2,
May
10,
2021
ABSTRACT: The COVID-19 pandemic has strained health systems
all over the world. The SARS-CoV-2 which causes the disease is a corona virus
that predominantly affects the respiratory systems. Since the outbreak of the
novel disease in December, 2019 the scientific world has intensified efforts to
elucidate its pathophysiology, mode of transmission, clinical manifestations,
best mode of prevention and treatment options. Very little is known about its
neuropathophysiology even though a significant number of patients come down
with obvious neurological signs and symptoms. The virus has been reported to
affect the nerves, muscles, the special senses and the central nervous system
with a wide range of clinical manifestations. The mechanisms by which the virus
causes all these are still not clear. This article
attempts to review and articulate all possible existing theories surrounding
the neurological effects of COVID-19.