TITLE:
A Novel Strategy for Preventing and Treating Cancer: Alteration of Cancer-Associated Chromatin Configuration
AUTHORS:
Gao-De Li
KEYWORDS:
Cancer, Cancer-Associated Chromatin Configuration (CACC), Non-Carcinogenic Genotoxic Drugs (NCGDs), Cancer Prevention, Cancer Treatment
JOURNAL NAME:
Open Access Library Journal,
Vol.8 No.5,
May
6,
2021
ABSTRACT: The hallmarks of cancer are determined by cancer-associated gene expression pattern that is determined by cancer-associated chromatin configuration (CACC). Using non-carcinogenic genotoxic drugs (NCGDs) to alter CACC could change cancer-associated gene expression pattern, which in turn, might cause disappearance of some or whole hallmarks of cancer and as a result, cancer cells could be killed by either apoptosis or immune destruction. Therefore, cancer could be prevented and treated by administration of NCGDs that can alter CACC in cancer cells.