TITLE:
Effects of Semi-Ablative Fractional Radiofrequency Associated with Growth Factors in Stretch Marks: A Randomized Controlled Trial
AUTHORS:
Patricia F. Meyer, Rodrigo Marcel V. Da Silva, Liliane S. Vasconcelos, Louhanne Christine B. Bezerra, Maria Paula M. Oliveira, Eneida M. Carreiro, Ciro D. Soares, Fabio S. Borges, Monica Etrusco, Joyce Rodrigues, Silene B. Ribeiro, Hernan Andrés B. Ortiz
KEYWORDS:
Striae Distensae, Collagen, Wound Healing
JOURNAL NAME:
Open Journal of Applied Sciences,
Vol.11 No.4,
April
13,
2021
ABSTRACT: Background: To investigate the effects of the association of semi-ablative fractional radiofrequency (RFF) with growth factors in stretch marks. Methods: This is a randomized controlled trial. The sample consisted of 28 female patients with complaints of gluteus or abdomen striae and divided into 2 equitable groups, named G1 (semi-ablative RFF without active principle association) and G2 (semi-ablative RFF with active principle association), being subdivided into G-1A and G-2A (abdominal applications) and G-1B and G-2B (gluteus applications). A photographic and histological analysis was performed using questionnaires about inflammation, presence of adverse effects and satisfaction of volunteers. Photographic analysis showed a reduction in the amount of striae alba in all groups. Results: The histological analysis showed an increase in fibroblast activity, collagen type I, and blood vessels, especially in the groups that associated the RFF with the active principle. In the inflammation analysis, the groups that performed intervention with active ingredients showed lower inflammatory signal. All groups had a reasonable level of satisfaction after the interventions; however, the group that used active ingredients reported greater results. Conclusion: The association of semi ablative RFF with growth factors showed a reduction in clinical inflammatory signs, mainly in the first 15 days, as well as higher collagen production, verified in 30 days, with satisfactory clinical results in all groups.