TITLE:
Intramedullary Metastasis of Medulloblastoma: A Case Report
AUTHORS:
Abderrazzak Bertal, Alberic Fabrice Bocco, Ismaïl Mahazou, Asmaa Harrach, Nihad da Silva, Mohamed Yassine Haouas, Khadija Ibahioin, Said Hilmani, Mehdi Karkouri, Abdelhakim Lakhdar
KEYWORDS:
Medulloblastoma, Intramedullary Metastasis, Classic, Spinal Cord
JOURNAL NAME:
Open Journal of Modern Neurosurgery,
Vol.11 No.2,
April
13,
2021
ABSTRACT: Medulloblastoma (MB) is a malignant brain tumor with a usual potential for leptomeningeal spread. Intramedullary metastases of MB are rare and there are very few cases reported in the literature. Here, we report the case of an 18-year-old man with intramedullary spinal cord metastasis of MB occurring 9 years after the first diagnosis. The patient presented a 2-month history of progressive weakness in both lower limbs associated with urinary incontinence. Magnetic resonance imaging (MRI) demonstrated a large intramedullary spinal cord tumor extending from T10 to L1. The patient underwent surgical decompression and adjuvant therapy. Histological examination confirmed the diagnosis of classic MB metastasis. Postoperatively, the neurological status was stationary. Intramedullary metastasis of medulloblastoma is rare and difficult to manage with a poor prognosis. Comprehensive studies on the medulloblastoma dissemination mechanisms and clinical trials are needed to assess combined therapeutic approaches on metastases of MB.