TITLE:
Prevalence, Risk Factors and Outcome of Preterm Premature Rupture of Membranes at the Bamenda Regional Hospital
AUTHORS:
Dobgima Walter Pisoh, Claude Hector Mbia, William Ako Takang, Obelda Guiswe Beltus Djonsala, Mbah Cypress Munje, Ascensius Achuo Mforteh, Dohbit Julius Sama, Robert John Ivo Leke
KEYWORDS:
Preterm PROM, Maternal Outcome, Perinatal Outcome, Associated Factors
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.11 No.3,
March
11,
2021
ABSTRACT: Background: Preterm premature rupture of membranes (PPROM) is one of the most common
complications of pregnancy. It is one of the leading identifiable cause of
preterm deliveries, and an important cause of maternal and perinatal morbidity
and mortality. The aim of this study was to determine the prevalence of
PPROM, to identify its associated factors and to evaluate the early outcome (within 72 hrs after delivery)
following PPROM at the Bamenda
Regional Hospital (BRH). Methods: A cross-sectional study was conducted in March and April 2020. Three hundred and eighty-seven women who
delivered at the labour room of the BRH were included in this study.
Interviewer-administered questionnaires were used to obtain data. The cases of
PPROM were women who had lost amniotic fluid continuously before
hospitalisation and whose gestational age was between 28 weeks + 0 days and 36
weeks + 6 days. Descriptive statistics followed by logistic regression analyses were conducted with level of significance
set at p-value Results: Among the 387 participants included in the study, 19 had
PPROM giving a prevalence of 4.91%. Of 57 preterm deliveries, PPROM
accounted for 33.33% (n = 19). The
statistically significant independent factors associated with lower odds
of PPROM were the age groups 20 - 29 years (aOR = 0.07, 95%
CI: 0.01 - 0.42, p = 0.003) and ≥30
years (aOR = 0.01, 95% CI: 0.001 - 0.14, p =
0.001), and attending ANC ≥ 4 times (aOR = 0.23, 95% CI: 0.06 - 0.84, p = 0.026). Whereas, having a multiple
pregnancy (aOR = 39.72, 95% CI: 7.19 - 219.33, p
- 897.90, p - 112.56, p = 0.003), and having a history of preterm
delivery (aOR = 27.65, 95% CI: 1.76 - 434.15, p
= 0.018) were associated with a higher
likelihood of PPROM. The study revealed that 10.53% (n = 2) of women who
had PPROM had an unfavourable outcome. Babies born by mothers who had PPROM
were more likely to have an unfavourable outcome (OR = 14.44, 95% CI: 5.42 - 38.48, p Conclusion: Preterm
premature rupture of membranes considerably causes perinatal morbidity and
mortality, and thus optimum obstetric and medical care is essential for the
reduction of the complications related to it.