TITLE:
Invasive Haemophilus influenzae Type b (Hib) Infections in Children in the Pediatric Department of the University Hospital Gabriel Touré (UH-GT)
AUTHORS:
B. Maiga, A. A. Diakité, K. Sacko, M. Sylla, M. Maiga, M. E. Cissé, A. Dembélé, F. Traoré, D. Konaté, F. L. Diakité, L. Sidibé, A. K. Doumbia, O. Coulibaly, P. Togo, A. Touré, K. Traoré, L. Maiga, A. Ibrahim, H. Diall, A. Doumbia, H. Konare, S. Sagara, M. Niakaté, A. Cissouma
KEYWORDS:
Invasive Bacterial Infections, Haemophilus influenzae b, Children, Pediatrics
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.11 No.1,
March
10,
2021
ABSTRACT: Introduction: According to Mali’s National Immunization Center,
the Haemophilus
influenzae b (Hib) vaccine
coverage rate was 90% in 2015. Our work aimed to study invasive
bacterial infections due to Haemophilus influenzae type b in children
aged 0 - 15 years hospitalized in the pediatrics department of the UH-GT. Method: We carried out a retrospective
descriptive study from January 2017 to December 2018 (i.e.
2 years) among children aged 0 - 15 years and hospitalized
for Haemophilus influenzae type b infection confirmed by culture (blood
culture, Cerebro-spinal Fluid, and pleural and skin fluid). Results: Thirty-three cases of Hib
infections were collected giving a frequency
of 0.2% and the age group 3 months to 3 years was the most affected
(72.73%). Children who received no vaccine accounted for
21.21%. The Cerebro-spinal Fluid culture and other samples (pleural and skin)
identified the bacterium in 100% of cases, against
72.72% in the blood culture Meningitis was the most frequent
pathology (78.79%) and the lethality was high (21.21%). Conclusion: Despite the
introduction of the Hib vaccine in the routine immunization program in Mali, Hib infections remain with a high
lethality linked to meningitis.