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Suzuki, T., Distante, A., Zizza, A., Trimarchi, S., Villani, M., et al. (2009) Diagnosis of Acute Aortic Dissection by D-Dimer. The International Registry of Acute Aortic Dissection Substudy on Biomarkers (IRAD-Bio) Experience. Circulation, 119, 2702-2707.
https://doi.org/10.1161/CIRCULATIONAHA.108.833004

has been cited by the following article:

• TITLE: Evaluation of D-Dimer as a Diagnostic Tool in Patients with Acute Aortic Dissection

  AUTHORS: Samir Rafla, Tarek Bishay

  KEYWORDS: Aortic Dissection, D-Dimer

  JOURNAL NAME: World Journal of Cardiovascular Diseases, Vol.11 No.2, February 24, 2021

  ABSTRACT: Acute (Ac.) Aortic Dissection (AD) is a life threatening cardiovascular emergency. The diagnostic methods (e.g., TEE, MRI, Multislice CT) are limited by availability. A fast, cost effective and technically simple method for diagnosis of AAD is needed. D-Dimer is a measure of clot formation and lysis. The aim of this study was to determine whether assessing D-Dimer level can be used for the diagnosis of AAD. Methods: 45 patients with clinical suspicion of AAD who presented within the first 24 hours from symptom onset were studied prospectively. 20 patients were proved to have AAD by TEE (group I). The other 25 patients had other final diagnosis (group II). All the 20 patients in group I (100%) with confirmed AAD had positive and elevated D-Dimer levels while only 9 patients in group II (36%) had positive D-Dimer levels (p Conclusion: D-Dimer levels are positive and elevated in all the patients with AAD presenting within the first 24 hours from symptom onset.