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Brandlein, S., Pohle, T., Ruoff, N., Wozniak, E., Muller-Hermelink, H.K. and Vollmers, H.P. (2003) Natural IgM Antibodies and Immunosurveillance Mechanisms against Epithelial Cancer Cells in Humans. Cancer Research, 63, 7995-8005.

has been cited by the following article:

• TITLE: Central Role of Innate B-Cell Immunity in Cancer Prevention

  AUTHORS: Nikolay Tupitsyn

  KEYWORDS: Natural B-Cell Immunity, Cancer Prevention, IgM, Anti-Glycans

  JOURNAL NAME: Advances in Biological Chemistry, Vol.11 No.1, February 2, 2021

  ABSTRACT: There are some forgotten items. There is a specific way to eradicate cancer cells at the very early stage of their appearance. Natural humoral immunity with CD5+ B-cell produced pentameric IgM to cancer associated glycans normally to eliminate arising cancer cells. This branch of innate immunity is decreasing with age and that is a basis for selective immunodeficieny which may be corrected. This area of research was well studied and proved by the team of Prof. Vollmers (Germany), but then forgotten for about 15 years.