TITLE:
Central Role of Innate B-Cell Immunity in Cancer Prevention
AUTHORS:
Nikolay Tupitsyn
KEYWORDS:
Natural B-Cell Immunity, Cancer Prevention, IgM, Anti-Glycans
JOURNAL NAME:
Advances in Biological Chemistry,
Vol.11 No.1,
February
2,
2021
ABSTRACT: There are some forgotten items. There is a specific way to eradicate cancer cells at the very early stage of their appearance. Natural humoral
immunity with CD5+ B-cell produced pentameric IgM to cancer associated glycans
normally to eliminate arising cancer cells. This branch of innate immunity is
decreasing with age and that is a basis for selective immunodeficieny which may
be corrected. This area of research was well studied and proved by the team of
Prof. Vollmers (Germany), but then forgotten for about 15 years.