TITLE:
The Association of Visceral Adiposity Index with Insulin Resistance in Adults with Prediabetes
AUTHORS:
Md. Shahed-Morshed, Tahniyah Haq, Md. Fariduddin, Sultana Parveen, Tohfa-E-Ayub, Naureen Mahbub, M. A. Hasanat
KEYWORDS:
Visceral Adiposity Index, Insulin Resistance, Prediabetes, Homeostatic Model Assessment of Insulin Resistance
JOURNAL NAME:
Open Journal of Endocrine and Metabolic Diseases,
Vol.11 No.1,
January
22,
2021
ABSTRACT: Visceral adiposity mediates insulin resistance, but their association among adults with prediabetes is scarce in the literature. This study is aimed to determine the association of visceral adiposity index (VAI) with insulin resistance in adults with prediabetes. This cross-sectional study was done among 117 adults with newly detected prediabetes [m/f; 23/94; mean ± SD: Age 36.30 ± 9.99 years, BMI 28.89 ± 4.35 kg/m2] based on American Diabetes Association 2018 criteria and 141 matched healthy controls [m/f: 28/113; mean ± SD: 35.30 ± 6.88 years, BMI 25.03 ± 4.58]. Waist circumference, body mass index, fasting triglyceride, HDL cholesterol, fasting blood glucose and insulin were measured in each group to calculate VAI and homeostatic model assessment of insulin resistance (HOMA-IR). People with prediabetes had significantly higher median value of VAI {3.08 (2.26) vs. 1.86 (2.31); p 1) (98.3% vs. 85.8%; p