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Abdulhameed, E.A., Enezei, H.H., Omar, M., Komori, A., Sugita, Y., Hegazy, F.A., Ari, S., Maeda, H. and Alam, M.K. (2017) The Effect of Low Intensity Pulsed Ultrasound Therapy on Osseointegration and Marginal Bone Loss Around Dental Implants. Journal of Hard Tissue Biology, 26, 323-330.
https://doi.org/10.2485/jhtb.26.323

has been cited by the following article:

• TITLE: The Effect of Material Surface Microstructure on the Enhancement of Bone-Bonding Ability of a Hydroxyapatite-Implant by Low-Intensity Pulsed Ultrasound (LIPUS)

  AUTHORS: Masanori Kobayashi

  KEYWORDS: Low-Intensity Pulsed Ultrasound (LIPUS), Simulated Body Fluid (SBF), Hydroxyapatite (HA), Osseointegration, Osteo-Conductivity

  JOURNAL NAME: Materials Sciences and Applications, Vol.12 No.1, January 20, 2021

  ABSTRACT: Excellent firm bonding between the biomaterials and bone tissue (osseointegration and osteo-conductivity) has been desired for the stability in vivo of dental implants and artificial joints. Much has been learned about this concept, which has led to significant improvements in the design and surface modification of implants in the field of implant dentistry, orthopedic surgery. We have already reported that low-intensity pulsed ultrasound (LIPUS) irradiation can accelerate the bone bonding ability of the bio-conductive materials such as bioactive titanium and hydroxyapatite implant. However, it is still unclear whether the LIPUS could have same effect to different types of the bioactive-materials. Therefore, in this study, the differences of bone-like hydroxyapatite formation on some kind of hydroxyapatite surface in simulated body fluid (SBF) under the LIPUS irradiation were investigated. Two kinds of hydroxyapatite samples immersed in SBF was exposed to ultrasound waves, the bone-like apatite on the surface was analyzed by Scanning electron microscopy and X-ray diffraction. As a result, the enhancement of hydroxyapatite formation on the surface by LIPUS was confirmed, the initial epitaxial nucleation and crystal growth of apatite depended on crystal structure of the surface of matrix materials.