TITLE:
Pediatric Nasopharyngeal Rhabdomyosarcoma: About a Case and Review of Literature
AUTHORS:
Dohoué Patricia Eliane Agbanglanon, Imane M’barki, Oswald Houessou, Gaël Kietga, Siham Jaba, Hafsa Elouazzani, Séka Evrard Narcisse, Hanan Elkacemi, Nadia Cherradi, Sanaa Elmajjaoui, Noureddine Benjaafar
KEYWORDS:
Rhabdomyosarcoma, Nasopharyngeal, Pediatric, Chemotherapy, Radiotherapy
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.12 No.1,
January
14,
2021
ABSTRACT: Introduction:Rhabdomyosarcoma (RMS) is the most common soft
tissue tumor in children, with the head and neck location accounting for up to
40% of cases. The embryonal and alveolar histologic variants are more commonly
seen in pediatric patients. The treatment is multimodal and the prognosis of
this clinical entity is always gloomy. We
report the case of nasopharyngeal rhabdomyosarcoma in a 7-year-old boy child
with a good response to early post-therapy. Case Presentation: The patient was diagnosed with nasopharyngeal RMS
revealed by a congested nose, ptosis and bilateral blindness, and who received
induction chemotherapy followed by concurrent radiotherapy followed by adjuvant
chemotherapy. The evolution is marked by a good clinical course but persistence
of bilateral blindness. Conclusion: The RMS nasopharyngeal often presents with
nonspecific symptoms. Multimodal therapy should be performed including surgery,
chemotherapy and radiotherapy.