Article citationsMore>>

Yakhno, T., Sanin, A., Pelyushenko, A., Kazakov, V., Shaposhnikova, O., Chernov, A., Yakhno, V., Vacca, C., Falcone, F. and Johnson, B. (2007) Uncoated quartz resonator as a universal biosensor. Biosensors and Bioelectronics, 22, 9-10, 2127-2131.

has been cited by the following article:

• TITLE: Protein phase instability developed in plasma of sick patients: clinical observations and model experiments

  AUTHORS: Tatiana Yakhno

  KEYWORDS: Protein Aggregation in Serum; Mechanisms of Inflammation

  JOURNAL NAME: Natural Science, Vol.2 No.3, April 12, 2010

  ABSTRACT: This article discusses the causes of formation of micron-size protein structures in liquid plasma or serum of the patients with different diseases, which are accompanied by inflammatory reac-tions. Self-organizing processes in sessile dry-ing drops of natural and model biological liq-uids are used for study of possible mechanisms of development the protein phase instability in serum. There was shown that violation of opti-mal ratio between albumin and osmotic active components could lead to loss of albumin ag-gregative stability and albumin coagulation structures formation. Possible role of these structures in pathogenesis of inflammation is discussed.